Focused across the Alzheimer’s continuum — from preclinical to advanced dementia — guided by scientific rigor, patient safety, and operational excellence.
MCMCR Neuroscience & Alzheimer’s Institute is an active ACTC member site, with leadership representation at the Steering Committee level.
Alzheimer’s Disease Trials by Stage
MCMCR conducts clinical trials across the Alzheimer’s disease spectrum, including:
Preclinical Alzheimer’s Disease
(Amyloid and/or tau biomarker-positive individuals without cognitive impairment)
Prodromal Alzheimer’s / Mild Cognitive Impairment (MCI)
due to Alzheimer’s
Mild to Moderate Alzheimer’s Dementia
Moderate to Severe Alzheimer’s Dementia
Neuropsychiatric and Behavioral Symptoms of Alzheimer’s Disease
(including agitation, apathy, psychosis, and mood disturbances)
Research Capabilities
Clinical & Biomarkers
- Brain MRI (3T) → Access to 3T Brain MRI with Alzheimer’s-specific protocol capability
- Dedicated infusion center
- Plasma biomarker sampling
- PET imaging (amyloid and tau) → Amyloid and tau PET imaging through certified imaging partners
- Dedicated, trained Alzheimer’s disease raters
- Lumbar puncture and cerebrospinal fluid (CSF) biomarker collection → PI-performed lumbar puncture and CSF biomarker collection
Operational
- Research pharmacy support (PharmD-led)
- Alzheimer’s disease principal investigators
- ACTC-experienced clinical research operations
- Participant recruitment and retention strategies
- Clinical research coordinators (CRCs) and research nurses
- Collaboration with imaging, laboratory, and specialty vendors
- ICH-GCP compliant operations
- Audit-ready SOP infrastructure
- Central IRB experience
- eSource / EDC proficiency
Strategic Partnerships & Research Collaborations
We welcome collaboration discussions with sponsors, CROs, and consortium networks.
Sponsors & CROs
Contact us to discuss feasibility, site capabilities, and collaboration opportunities.
ACTC affiliation is provided for informational purposes only and does not imply endorsement of specific clinical trials or sponsors.
MCMCR Alzheimer’s Research Highlights
Interested in Participating in an Alzheimer’s Research Study?
Individuals and families may be eligible to participate in Alzheimer’s disease clinical research studies depending on memory symptoms, medical history, and biomarker status. Participation is voluntary and all studies are conducted under strict ethical and regulatory oversight.
Contact us to learn more about current research opportunities.
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